宫颈鳞状细胞癌
2Survivin的表示和宫颈癌组织学分级、浸润深度、临床分期相关P;
PTEN蛋白的表示和宫颈癌浸润深度、临床分期相关P;
3Survivin和PTEN蛋白在癌旁不经典增生和慢鳞的表示阳性率差异都有显著性P
和CIN相比差异无显著性P>;
4Survivin和PTEN蛋白的表示在CIN、癌旁组织、中的表示呈显著负相关P
摘要癌旁组织CINSurvivinPTEN免疫组织化学AbstractObjectiveThepurposeofthispaperistoanalyzetheexpressionandtherelationshipofapoptosisinhibitionfactorSurvivinandcarcinoma-inhibitingproteinPTENincervicalcancer,adjacentmucosaandprecancerouslesionsanddiscusstheexpressionofSurvivinandPTENontheoccurrenceanddevelopmentofcervicalusingtTheimmunoassayS-PmethodwasusedtodeterminedetectthepositiverateofSurvivinandPTEN,.wechoose135caseswithofchroniccervicitisincluding20caseswithofcervcalierosionofmetaplasiaCCM20,cervicalintraepithelialneoplasiaCIN31,cervicalcarcinoma42,adjacentmucosa42,withanotherand10casesofnormalcervicalspecimensasthereferencecontrolwere1Tocervixcancer,cervicalcarcinomaandadjacentmucosa,theexpressionofCCMand,SurvivinexpressiontendstoincreasedWilcoxontestP
theexpressionofPTENtendstodecreasedP;PTENwasrelatedwiththepatients’infiltrationdepth,,butwithoutstatisticsmeaningascomparingcompariedwithCINP>.4TheexpressionofSurvivinandPTENwasextremelynegativelycorrelatedinCINand,cervicalcancer,andadjacentmucosaP
adjacentmucosa;
CIN;
Survivinand;
PTEN;
immunohistoch
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