钌宝宝的自荐信--我是抗癌小战士.pdf

Univ. Chem. 2019, 34 (8), 47−50 47
 
•科普• doi:
钌宝宝的自荐信
——我是抗癌小战士

马文，贾卫国*
安徽师范大学化学与材料科学学院，安徽 芜湖 241002

摘要：采取拟人化的手法，以第一人称介绍了钌元素的发现历史，重点阐述了钌配位化合物在抗肿瘤药物方面的应
用。详细介绍了在临床或已经进行临床试验的抗肿瘤试剂如KP1019等，以及具有半夹心钌结构的配位化合物及钌多吡
啶类的药物。

关键词：钌；配合物；抗癌
中图分类号：G64；O614

Self-Recommendation Letter of Baby Ruthenium: I Am an
Anticancer Warrior

MA Wen, JIA Weiguo *
College of Chemistry and Materials Science, Anhui Normal University, Wuhu 241002, Anhui Province, P. R. China.

Abstract: Using the anthropomorphic approach, this article introduces the discovery history of ruthenium elements
in the first person role, and focuses on the ruthenium complexes as important therapeutic agents for cancer treatment.
We have focused our attention on KP1019 incorporating ruthenium ions complexes which have been already used in
clinical or have been advanced to clinical trials as anticancer agents. Moreover, the half-sandwich ruthenium and
ruthenium polypyridine complexes drugs are also reviewed.

Key Words: Ruthenium; Complex; Anticancer

亲爱的人类：
你们好！我是钌，铂系家族的一员，你们也可以叫我的英文名“Ruthenium”。这是我第一次主
动给你们写信，有点小紧张，希望你们读完之后可以更加了解和喜欢我！