木疏胶囊抗大鼠肝纤维化免疫机制研究.pdf

俗、、黜/^陌删·硼7·BEIJING·C哪M The immunologic mechanism fortheantifibrotic action of Mushu Capsule on rats PingGao,Department ofOncology,General Hospital ofChinese PLA,Beijing 100853,China Liu-Fang Cheng,Department ofGastroenterology,General Hospital ofChinese PLA,Beijing 100853,China Ze—Yong Shao,the AffiliatedHospital ofLuzhou Medical College,Luzhou 646000,Sichuan Province,China Correspondence to:Liu-Fang Cheng,Department ofGastroenterology, General Hospital ofChinese PLA,28 FuxingRoad,Beijing 100853, China.******@ ABSTRACT AIM:To investigate theeffectofMushu capsule on thehumoral immunity and cellimmunity of Methods:Wistar ratswere randomly divided into4groups:normal controlgroup,model group,mushu capsule group andruanganpian capsule andruanganpian group was subdivided intoprevention group fibrosismodel was induced by subcutaneous injection L4 f40%density, bodyweight)twice aweek foreight inprevention group were givendrugs atfirstinjection L, .Ratsintreatment group were given drugs afterinjection theend the rats were ratblood was drawn from theheartandtheliverswere ofserum interleukin(IL)2,6,8 andtumor necrosisfactor-QfiNE-Q)were performed,at thesame time,tissue sections were stainedrespectivelythrough HE andMasson andmicro featureschanges ofth