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Perfect works with bination Lusheng Wang Dept. puter Sci. City Univ. of Hong Kong83 Tat Chee Avenue Hong Kong ******@ Kaizhong Zhang Dept. puter Sci. Univ. of Western OntarioLondon, Ont. N6A 5B7 Canada ******@ Louxin Zhang BioInformatics Centre Nat. Univ. of Singapore 21 Heng Mui Keng TerraceSingapore 119613 ******@ ABSTRACT 1. INTRODUCTION Permission to make digital or hard copies of part or all of this work or personal or classroom use is granted without fee provided that copies are not made or distributed for profit mercial advantage and that copies bear this notice and the full cita tion on the first page. To copy otherwise, to republish, to post on server