益肾化瘀汤联合中药免疫抑制剂治疗慢性肾炎患者及对尿蛋白、肾纤维化的影响.doc

益肾化瘀汤联合中药免疫抑制剂治疗慢性肾炎患者及对尿蛋白、肾纤维化的影响
摘要 目的:探討益肾化瘀汤联合中药免疫抑制剂治疗慢性肾炎患者的临床疗效及对尿蛋白、肾纤维化的影响。方法:选取2016年1月至2017年12月周口市中医院收at of the control group (%), and the difference was statistically significant (P<). There was no significant difference in urine protein quantitation, Scr, BUN, LN, PC-III, Col-IV and TIMP-1 levels between the two groups before treatment (P>). Urinary protein quantification, Scr, BUN, LN, PC-III, Col-IV and TIMP-1 levels in the two groups were significantly decreased after treatment (P<). The levels of urine protein, Scr, BUN, LN, PC-III, Col-IV and TIMP-1 in the observation group were significantly lower than those in the control group, and the difference was statistically significant (P<). There was no significant difference in clinical adverse reactions between the two groups (P>). Conclusion:Yishen Huayu Decoction combined with traditional Chinese medicine immunosuppressant can significantly reduce the amount of urine protein in patients with chronic nephritis, improve renal function index, reduce the serum LN, PC-III, Col-IV and TIMP-1 renal fibrosis indexes, delay the process of renal fibrosis. The clinical effect is significant, and can be further applied. Key Words Yishen Huayu Decoction; Chinese medicine; Immunosuppressive agents; Tripterygium wilfordii glycosides; Chronic glomerulonephritis; Urinary protein; Renal fibrosi