医药导报 年 月第 卷第 期
2022 5 41 5 DOI 开放科学 资源服务 标识码 OSID
/  ̄ ( ) ( )
Application of Solid ̄state Nuclear Magnetic Resonance Technology in the Research of
Crystalline Drugs
Beijing Key Laboratory of Polymorphs
CHEN TingꎬLI QiꎬLIU QiwenꎬYANG ShiyingꎬZHANG LiꎬLYU Yang(
Drugs Research Institute of Materia Medical Chinese Academy of Medical Sciences Peking Union Medical
ꎬ ꎬ ꎬ
College Beijing China
ABꎬSTRACT100050ꎬ )
Many active pharmaceutical ingredients are used in the form of solid preparations. In order to improve the
solubilityꎬstabilityꎬ and bioavailability of the drugꎬ it is necessary to study and characterize the polymorphꎬ cocrystalꎬ and
amorphous form of the application of solid ̄state nuclear magnetic resonance technology in the field of drug analysis has
become more and more in ̄depthꎬand its qualitative and quantitative advant
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