中药丹参的现代化研究进展 马晓晶.pdf

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中国中药杂志制剂展开了应用研究。该文系统地总结了丹参及其活性成
分相关的现代化研究进展，重点介绍了丹参活性成分的药理作用、制剂研究、生物合成及调控机制研究，相关研究的
现代化技术手段和研究思路具有一定的普适性，期望能够进一步发挥丹参在中药研究中的模式作用。
关键词 丹参；合成生物学；丹参基因组；丹参***；丹酚酸
DOI: .
Modernization of Chinese medicine Radix Salviae Miltiorrhizae: A Review
MA Xiao-jing1 , YANG Jian1 , MA Gui-rong2 , ZENG Wen1 , GUO Juan1 , MA Ying1 
(1. State Key Laboratory Breeding Base of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical
Sciences, Beijing 100700, China;
2. Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China)
Abstract Modernization of Chinese medicine is an important development direction of traditional Chinese medical
sciences. It is of great significance to understand the mechanism of Chinese medicine with basic research, which can also
accelerate the development and utilization of Chinese medicine. Radix Salviae Miltiorrhizae is one of the most commonly
used Chinese medicines in China for the prevention and treatment of cardiovascular and cerebrovascular diseases. It has
received key and extensive attention worldwide in the following aspects: main active ingredients and their pharmacological
mechanism, function and regulation of their biosynthetic pathway and application of their synthetic biology as well as the
clinical preparations. The new and developing chemical analysis, network pharmacology, molecular pharmacognosy and
omics make the modernization research of Radix Salviae Miltiorrhizae comprehensive and in-depth. This study systematically
reviewed the modernization research of Radix Salviae Miltiorrhizae, which focused on its pharmacological effects,
preparation resea