1—Modulation of DNA repair capacity and mRNA expression levels of 1, hOGG1.pdf

Toxicology and Applied Pharmacology 248 (2010) 194–200
Contents lists available at ScienceDirect
Toxicology and Applied Pharmacology
journal homepage: ate/ytaap
Modulation of DNA repair capacity and mRNA expression levels of 1, hOGG1
and XPC genes in styrene-exposed workers
Monika Hanova a,b, Rudolf Stetina c, Ludmila Vodickova a,d, Radka Vaclavikova d, Pavel Hlavac e,
Zdenek Smerhovsky d,f, Alessio arati a, Veronika Polakova a, Pavel Soucek d, Miroslava Kuricova g,
Paola Manini h, Rajiv Kumar i, Kari Hemminki i, Pavel Vodicka a,⁎
a Institute of Experimental Medicine, Academy of Sciences of Czech Republic, Prague, Czech Republic
b Department of ics and Microbiology, Faculty of Science, Charles University, Prague, Czech Republic
c Purkynje Military Medical Academy, Hradec Kralove, Czech Republic
d National Inst. Public Health, Prague, Czech Republic
e Dept. Occup. Medicine at Regional Hygiene Station, Hradec Kralove, Czech Republic
f 2nd Medical Faculty, Charles University, Prague, Czech Republic
g Res. Base, Slovak Medical Univ., Bratislava, Slovak Republic
h Dept. of Clinical Medicine, Nephrology and Health Sciences, University of Parma, Italy
i German Cancer Research Center (Deutsches Krebs Forschungs Zentrum; DKFZ), Heidelberg, Germany
article info abstract
Article history: Decreased levels of single-strand breaks in DNA (SSBs), reflecting DNA damage, ha