Association between polymorphism in the insulin receptor-related receptor gene and growth traits in the Pacific oyster Crassostrea gigas.pdf.pdf

Biochemical Systematics and Ecology 54 (2014) 144–149
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Biochemical Systematics and Ecology
journal homepage: ate/biochemsyseco
Association between polymorphism in the insulin receptor-
related receptor gene and growth traits in the Pacific oyster
Crassostrea gigas
Rihao Cong, Lingfeng Kong, Hong Yu, Qi Li*
Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266003, China
article info abstract
Article history: Insulin receptor-related receptor (IRR) is an orphan receptor tyrosine kinase of the insulin
Received 21 October 2013 receptor family, and involved in the growth and reproduction processes of the Pacific
Accepted 1 February 2014 oyster Crassostrea gigas. Polymorphisms of the IRR gene were evaluated for associations
Available online 20 February 2014
with growth performance of 336 individuals in five families, and further confirmed in 206
individuals from three selectively bred strains for fast growth. Two of the six identified
Keywords: synonymous mutations ( > A and > T) were significantly associated with
Crassostrea gigas
growth performance in the families and strains. Five diplotypes were constructed based on
Insulin receptor-related receptor
Growth trait the two growth-related SNPs, and diplotypes analysis revealed that D3 (GGTT) might be
SNP the most advant