Clinical profile of patients using normal, high and very high insulin doses in type 2 diabetes.pdf.pdf

Diabetes & Metabolic Syndrome: Clinical Research & Reviews 8 (2014) 72–74

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Original Article

Clinical profile of patients using normal, high and very high insulin

doses in type 2 diabetes

. Hari Kumar *, . Gupta, Amit Kumar

Department of Endocrinology, Command Hospital, Lucknow 226002, ., India

A R T I C L E I N F O A B S T R A C T

Keywords: Aims: Insulin requirement varies between patients with diabetes due to insulin resistance. The clinical


Type 2 diabetes profile of patients based on their insulin requirement has not been studied earlier. We stratified the
Insulin resistance

patients based on total daily insulin requirement (TDIR) and studied their clinical profile and

High insulin requirement
carbohydrate consumption.
Insulin dose

Materials & methods: Sixty patients with type 2 diabetes (aged 30–75 years, using stable insulin dose for

last 6 months, HbA1c between 6– %, negative screening tests for Acromegaly and Cushing’s disease)

participated in this clinical observational study. All patients with major illness, surgery or diabetic

ketoacidosis were excluded. The patients were divided into 3 groups: Group 1 (TDIR <1 U/kg, n = 30),

Group 2 (TDIR 1–2 U/kg