Determinants of C-peptide levels and acute insulin resistancesensitivity in nondiabetic STEMI role of Killip class.pdf.pdf

IJC Metabolic & Endocrine 2 (2014) 35–38
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IJC Metabolic & Endocrine
journal homepage: /ijc-metabolic-and-endocrine
Determinants of C-peptide levels and acute insulin resistance/sensitivity in nondiabetic
STEMI role of Killip class
Chiara Lazzeri ⁎,Serafina Valente, Maria Grazia D'Alfonso, Marco Chiostri, Gian Franco Gensini
Intensive Cardiac Coronary Unit, Heart and Vessel Department, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
article info abstract
Article history: The alterations in glucose homeostasis in the early phase of nondiabetic ST-elevation myocardial infarction
Received 16 November 2013 (STEMI) plex, involving not only hyperglycemia but also the development of acute insulin resistance
Received in revised form 2 February 2014 (as part of the stress response) as assessed by the Homeostatic Model Assessment index (HOMA). No data is
Accepted 4 February 2014
so far available on C-peptide values in the acute phase of STEMI in patients without previously known diabetes.
Available online 14 February 2014
The aims of the present investigation, performed in 782 consecutive STEMI patients without previously known
Keywords: diabetes, were as follows: a) to assess the determinants of C-peptide levels; b) to address the relation between
ST-elevation myocardial infarction acute insulin-resistance and Killi