Effect of continuous positive airway pressure on insulin growth factor-1 in patients with obstructive sleep apnea A meta-analysis.pdf.pdf

Growth Hormone & IGF Research 25 (2015) 75–79
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Growth Hormone & IGF Research
journal homepage: ate/ghir
Effect of continuous positive airway pressure on insulin growth factor-1
in patients with obstructive sleep apnea: A meta-analysis
Li-Da Chen a,1,LiLina,1, Jie-Feng Huang b,1, Xiao Chen b, Qiao-Zhen Xu a,Jian-NanLiua,⁎
a Department of Respiratory Medicine, Zhangzhou Affiliated Hospital of Fujian Medical University, No. 59, Shenglixi Road, Xiangcheng District, Zhangzhou, Fujian Province 350005,
People's Republic of China
b Department of Respiratory Medicine, the First Affiliated Hospital of Fujian Medical University, No. 20, Chazhong Road, Taijiang District, Fuzhou, Fujian Province 350005, People's Republic of China
article info abstract
Article history: Objective: Obstructive sleep apnea (OSA) has been recognized as being associated with low level of insulin
Received 27 September 2014 growth factor-1 (IGF-1). However, the impact of OSA treatment using continuous positive airway pressure
Received in revised form 15 December 2014 (CPAP) on IGF-1 remains controversial. We performed a meta-analysis to determine whether effective CPAP
Accepted 18 December 2014 therapy could increase IGF-1 levels.
Available online 27 December 2014
Design: Two reviewers independently searched PubMed, Cochrane library, Embase and Web of Scien