分次立体定向放射治疗在鼻咽癌中的应用.doc

分次立体定向放射治疗在鼻咽癌中的应用
【摘要】目的探讨分次立体定向放射治疗(FSRT)在鼻咽癌冶疗中的作用及意义。方法 2008年6月至2010年11月用FSRT技术治疗鼻咽癌患者18例(初治者8例,复发者10例)。初治患者先行常规外照射40~50Gy,再行FSRT补量照射至75~80Gy。复发患者均行FSRT照射以85%~90%等剂量曲线包绕靶区周边。结果初治患者治疗后症状均有改善并全部存活,中位生存期9个月。复发患者中2例因肿瘤广泛侵犯症状无改善外其余症状均明显改善存活3例,中位生存期6个月。结论 FSRT技术是治疗鼻咽癌的一种全新的途径,它提高了肿瘤的局控率并降低了放疗后并发症的发生率。
【关键词】分次立体定向放射治疗鼻咽癌常规外照射
【Abstract】Objiectives: To evaluate the effect and sense of fractionated stereotactic radiotherapy (FSRT) in the treatment of nasopharyngeal carcinoma .Methods: Eighteen patients with nasopharyngeal carcinoma were treated with FRST between june 2000 and November 2002. After dose of 4o~45Gy external irradiation ,These previously untreated patients(8case) received FSRT booster dose to a total dose 75~80Gy. In the recurrent patients(10case),they were all treated with fractionated stereotactic radiotherapy by 85%~90% isodose line to the periphery of the : The previously untreated patients were alive,media survive after FSRT was 9 months. The syndrome of 8 recurrent
patients was improved ,wih 3 patients still living. Meanwhile it of 2 recurrent patients wasn,t improved for tumor : Fractionated stereotactic radiotherapy (FSRT) provide pletely new approach to the local and reduce the plications.
【Keywords】Fractionated Stereotactic Radiontherapy Nasopharyngeal carcinoma Conventional external beam irradiation
现阶段放射治疗是鼻咽癌首选的