【关键词】小脑;血管母细胞瘤;磁共振成像;病理学 [ABSTRACT] Objective To analyze the association between MRI and pathological manifestations of HippelLindan syndrome (HP syndrome). Methods A retrospective study was done in 27 cases of HP syndrome confirmed pathologically, of which their MRI and pathological findings were analyzed. Results On MRI: 19 were large cysticwithsmallnodule type, seven solidmass type, and one purelycystic. On T1weighted imaging (T1WI), the cystic part of the tumor showed welldistributed low signal intensity, the nodule or the solid part showed slightly low signal intensity or isointensity; On T2WI and FLAIR, the cystic part displayed evenlyhigh intensity, and the nodules or the solid mass manifested a slightly high signal intensity. The nodules or the solid part could be significantly enhanced. The nodules or the solid mass posed of interstitial cells, while the cysts were mainly work. Conclusion The MRI of HippelLindan syndrome is characteristic that closely related to its pathology, which is an effective method for the diagnosis of the