C-反应蛋白联合WBC分类检测在小儿感染中的临床应用.doc

C-反应蛋白联合WBC分类检测在小儿感染中的临床应用
【摘要】目的:研究C-反应蛋白(CRP)、白细胞分类计数联合检测在儿科感染性疾病中的应用价值。
方法:儿科183例住院感染性疾病患儿分别测定CRP和WBC分类计数,同时检测30例健康体检儿童为对照组。
结果:细菌感染组与病毒感染组、对照组比较其CRP和白细胞计数明显升高,有显著性差异(P<),且白细胞升高以中性粒细胞升高为主的占较大比例。
结论:在小儿感染性疾病中,联合检测WBC与CRP有助于小儿疾病的早期鉴别诊断,尤其是CRP敏感,快速,阳性率较高。
【关键词】 C-反应蛋白; WBC分类计数; 细菌感染; 病毒感染
Application bined detection of C-reactive protein and WBC in Pediatric infectious diseases
【ABSTRACT】 Objective: To study the value of detection of CRP and Leukocyte count in pediatric infectious diseases.
Methods: Total 183 cases of hospitalized children with infection were determined whole blood CRP level and WBC count respectively, simultaneous determination of 30 healthy children as the control group.
Results:The CRP and leukocyte count in the bacterial infection group were significantly higher than the virus infection and the control group, and the difference was statistically significant(P<). Neutrophils mainly increased in the bacterial infection group.
Conclusions: Combined detection of CRP and WBC in patients is beneficial for differential diagnosis of pediatric infectious disease early.
【Key words】 C-reactive protein; leukocyte count; bacterial infection; virus infection
前言
儿童感染性疾病是临床最常见的疾病之一,以细菌感染与病毒感染多见,两者的临床症状相似,故疾病早期对于两者的鉴别有一定难度。确诊须经过细菌培养或病毒分离,但其操作复杂,耗时且阳性率低,往往延误诊治,白细胞分类计数与CRP联合检测应用于临床,主要是有助于疾病早期鉴别诊断。可进一步指导临床医师合理选用抗感染的药物并判断疗效,避免抗生素滥用。CRP是急性炎症期最为灵敏的急性时相反应蛋白,影响