琥乙红霉素颗粒剂说明书(英文).pdf

.®

(ERYTHROMYCIN ETHYLSUCCINATE)
Rx only





To reduce the development of drug-resistant bacteria and maintain the effectiveness of
. and other antibacterial drugs, . should be used only to treat or prevent
infections that are proven or strongly suspected to be caused by bacteria.

DESCRIPTION
Erythromycin is produced by a strain of Saccharopolyspora erythraea (formerly
Streptomyces erythraeus) and belongs to the macrolide group of antibiotics. It is basic
and readily forms salts with acids. The base, the stearate salt, and the esters are poorly
soluble in water. Erythromycin ethylsuccinate is an ester of erythromycin suitable for oral
administration. Erythromycin ethylsuccinate is known chemically as erythromycin 2'­
(ethylsuccinate). The molecular formula is C43H75NO16 and the molecular weight is
. The structural formula is:




. Granules are intended for reconstitution with water. Each 5-mL
teaspoonful of reconstituted cherry-flavored suspension contains erythromycin
ethylsuccinate equivalent to 200 mg of erythromycin.
The pleasant tasting, fruit-flavored liquids are supplied ready for oral
administration.
. 200 Liquid: Each 5-mL teaspoonful of fruit-flavored suspension contains
erythromycin ethylsuccinate equivalent to 200 mg of erythromycin.
. 400 Liquid: Each 5-mL teaspoonful of orange-flavored suspension