呼吸内科医学论文.doc

肺癌化疗患者并下呼吸道感染临床特点及影响因素分析信息推荐:医学论文发表——创新医学网/ 作者:焦克岗,戴月梅,孙峰,夏栖,吐汗,祖龙,黄学焕, 齐曼古丽作者单位: 830054 新疆乌鲁木齐, 新疆医科大学第一附属医院呼吸科【摘要】目的观察肺癌患者化疗期间合并下呼吸道感染情况, 从而为下一步治疗提供有效的预防措施。方法经病理学或细胞学证实的 436 例肺癌患者给予铂类为主的化疗, 大部分接受 4~6 个疗程, 个别接受 6 个以上疗程。结果全组肺癌患者共 436 例,其中合并下呼吸道感染 123 例, 感染发生率为 % 。且症状不典型。X 线特征为小片状或大片浸润样阴影阻塞性肺炎和肺不张。结论肺癌患者化疗期间合并下呼吸道感染几率高, 且与化疗次数相关联, 故在肺癌化疗期间应及早加强免疫支持治疗。【关键词】肺癌; 化学疗法; 下呼吸道感染 Analysis of clinical features and affecting factors on the patients with lung cancer using plicated with lower respiratory infection JIAO Ke-gang , DAI Yue-mei , SUN Feng , et of Respiratory Diseases , The First Affiliated Hospital , Xinjiang Medical University , Urunqi 830054 , China. [Abstract] Objective To observe the lower respiratory infection status of patients with lung cancer during the period of chemotheraoy , in order to provide the further effective prevention measures for the following Four hundred and thirty-six patients with lung cancer confirmed by pathology received platinum-based chemotherapy , most of the patients received the chemotherapy for 4~ 6 cycles , others for more than 6 One hundred and twenty-three patients plicated with lower respiratory infection with atypical incidence rate of lower respiratory infection was %.X-rays showed small or big patchy , ill-defined shadowing (obstructive pneumonia or collapsed lung).Conclusion The incidence rate of lower respiratory infection increases in patients with lung cancer using chemotherapy , which is closely associated with the times of early stage , immune and support therapy is important in the period of chemotherapy. [Key words] lung cancer;chemotherapy;lower respiratory infection 肺癌发病率逐年递增, 已成为呼吸系统的常见病, 早期诊断困难, 确诊时大多数为晚期, 化学治疗( 简称化疗) 是目前治疗肺癌主要方法之一, 它使大多数肺癌患者从中受益, 但也不可避免地造成患者免疫功能损害, 增加了肺部感染机会, 明显影响肺癌患者的预后, 因此早期诊断和合理治疗具有极其重要意义。现对我院 2000 年以来肺癌患者伴肺部感染者进行回顾性分析, 目的是探讨肺癌患者伴下呼吸道感染的临床特征并指导临床治疗。 1 资料与方法 一般资料 2000 ~ 2004 年我科共收治经组织学或细胞学证实肺癌患者 436 例, 其