Dietary glycemic load, insulin load, and weight loss in obese, insulin resistant adolescents RESIST study.pdf.pdf

Clinical Nutrition 34 (2015) 89e94
Contents lists available at ScienceDirect
Clinical Nutrition
journal homepage: ate/clnu
Original article
Dietary glycemic load, insulin load, and weight loss in obese, insulin
resistant adolescents: RESIST studyq
Gesa Joslowski a,b,*, Jocelyn Halim a, Janina Goletzke b, Megan Gow a,c, Mandy Ho c,
Jimmy C.-Y. Louie d, Anette E. Buyken b, Chris T. Cowell a,c,e, Sarah P. t a,c,e
a Institute of Endocrinology and Diabetes, The Children’s Hospital at Westmead, Sydney, Australia
b IEL-Nutritional Epidemiology, University of Bonn, DONALD Study at the Research Institute of Child Nutrition, Germany
c The Children’s Hospital at Westmead Clinical School, University of Sydney, Sydney, Australia
d Faculty of Science, Medicine and Health, The University of Wollongong, Australia
e Kids Research Institute at the Children’s Hospital at Westmead, Sydney, Australia
article info summary
Article history: Background & aims: The optimal dietary approach for weight loss and improving insulin sensitivity in
Received 7 November 2013 adolescents is unknown. This study aimed to explore the association between the estimated insulin
Accepted 20 January 2014 demand of the diet, as measured by glycemic and insulin load, weight loss, percentage body fat and
insulin sensitivity index (ISI) in obese adolescents with clinical features of insulin resistance a