In the Golden Age of Organocatalysis有机催化的黄金时代.pdf

Reviews P. I. Dalko and L. Moisan
Asymmetric Catalysis
In the Golden Age of Organocatalysis**
Peter I. Dalko* and Lionel Moisan
Keywords:
asymmetric catalysis · chiral auxiliaries ·
organocatalysis · synthetic
methods
Angewandte
Chemie
5138  2004 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim DOI: Angew. Chem. Int. Ed. 2004, 43, 5138 – 5175
Angewandte
Organocatalysis Chemie
The term “organocatalysis” describes the acceleration of chemical From the Contents
reactions through the addition of a substoichiometric quantity of an
organic compound. The interest in this field has increased spectacu- 1. Introduction 5139
larly in the last few years as result of both the novelty of the concept 2. Reactions via Covalent
and, more importantly, the fact that the efficiency and selectivity of Transition Complexes 5140
many organocatalytic reactions meet the standards of established
organic reactions. Organocatalytic reactions are becoming powerful 3. Reactions via Noncovalent
tools in the construction of complex molecular skeletons. The diverse Activation Complexes 5158
examples show that in recent years organocatalysis has developed 4. Enantioselective Phase-Transfer
within organic chemistry into its own subdiscipline, whose “Golden Reactions[195] 5164
Age” has already dawned.
5. Asymmetric Transformations in
a Chiral Cavity 5168